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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIN1
All Species:
8.79
Human Site:
S43
Identified Species:
13.81
UniProt:
Q13526
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13526
NP_006212.1
163
18243
S43
R
P
S
G
N
S
S
S
G
G
K
N
G
Q
G
Chimpanzee
Pan troglodytes
XP_001161914
174
19574
S43
R
P
S
G
N
S
S
S
G
G
K
N
G
Q
G
Rhesus Macaque
Macaca mulatta
XP_001099116
145
16071
N26
S
G
R
V
Y
Y
F
N
H
I
T
N
A
S
Q
Dog
Lupus familis
XP_542080
163
18285
S43
R
P
S
G
N
S
S
S
G
S
K
N
G
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QUR7
165
18352
G45
S
G
G
S
T
V
G
G
S
S
K
N
G
Q
G
Rat
Rattus norvegicus
NP_001100171
165
18314
G45
S
G
G
S
T
V
G
G
G
S
K
N
G
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089028
159
17622
A39
S
Q
W
E
R
P
T
A
G
G
K
N
G
Q
G
Zebra Danio
Brachydanio rerio
NP_957042
159
17688
G39
S
Q
W
E
R
P
S
G
S
G
A
D
G
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54353
166
18358
G46
E
P
A
K
K
A
G
G
G
S
A
G
G
G
D
Honey Bee
Apis mellifera
XP_624205
162
18033
P42
R
P
D
K
P
A
D
P
S
G
N
N
K
G
D
Nematode Worm
Caenorhab. elegans
NP_494393
168
19158
K48
F
G
K
G
S
E
L
K
S
V
Q
C
L
H
L
Sea Urchin
Strong. purpuratus
XP_788025
152
17114
W33
M
A
S
K
E
S
R
W
D
K
P
E
G
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SL42
119
12996
Baker's Yeast
Sacchar. cerevisiae
P22696
170
19386
H50
G
T
N
K
D
Q
L
H
K
H
L
R
D
H
P
Red Bread Mold
Neurospora crassa
O60045
182
20596
Q62
H
S
P
T
S
Q
Q
Q
Q
Q
Q
Q
Q
Q
Q
Conservation
Percent
Protein Identity:
100
93.6
81.5
98.7
N.A.
95.1
95.7
N.A.
N.A.
N.A.
86.5
79.1
N.A.
56
65
57.1
55.2
Protein Similarity:
100
93.6
84
98.7
N.A.
96.9
96.9
N.A.
N.A.
N.A.
93.8
88.9
N.A.
65
74.8
67.2
70.5
P-Site Identity:
100
100
6.6
93.3
N.A.
33.3
40
N.A.
N.A.
N.A.
46.6
26.6
N.A.
20
26.6
6.6
20
P-Site Similarity:
100
100
13.3
93.3
N.A.
33.3
40
N.A.
N.A.
N.A.
60
33.3
N.A.
33.3
33.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.1
44.1
50.5
Protein Similarity:
N.A.
N.A.
N.A.
53.9
60.5
63.7
P-Site Identity:
N.A.
N.A.
N.A.
0
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
0
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
14
0
7
0
0
14
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
7
0
7
0
7
0
7
0
0
7
7
0
14
% D
% Glu:
7
0
0
14
7
7
0
0
0
0
0
7
0
0
0
% E
% Phe:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
7
27
14
27
0
0
20
27
40
34
0
7
60
14
47
% G
% His:
7
0
0
0
0
0
0
7
7
7
0
0
0
14
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
7
27
7
0
0
7
7
7
40
0
7
0
0
% K
% Leu:
0
0
0
0
0
0
14
0
0
0
7
0
7
0
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
20
0
0
7
0
0
7
54
0
0
0
% N
% Pro:
0
34
7
0
7
14
0
7
0
0
7
0
0
7
14
% P
% Gln:
0
14
0
0
0
14
7
7
7
7
14
7
7
47
14
% Q
% Arg:
27
0
7
0
14
0
7
0
0
0
0
7
0
0
0
% R
% Ser:
34
7
27
14
14
27
27
20
27
27
0
0
0
7
0
% S
% Thr:
0
7
0
7
14
0
7
0
0
0
7
0
0
0
0
% T
% Val:
0
0
0
7
0
14
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
14
0
0
0
0
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _